Efficient DNA pairing in a Neurospora mutant defective in chromosome pairing |
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| Authors: | Henriette M. Foss and Eric U. Selker |
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| Affiliation: | (1) Institute of Molecular Biology, University of Oregon, 97403 Eugene, OR, USA |
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| Abstract: | Summary A Neurospora crassa mutation, mei-2, affecting recombination and pairing of homologous chromosomes during meiosis, was characterized for its effect on repeat-induced point mutation (RIP). We found that RIP, which depends on recognition of DNA sequence homology, is not inhibited by mei-2, suggesting that the defect in chromosome pairing of this mutant is not due to a defect in DNA pairing and that DNA pairing is not dependent on chromosome pairing. |
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| Keywords: | Neurospora Repeat-induced point mutation (RIP) Recombination Synapsis DNA pairing |
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