Effect of exhaustive exercise on liver mitochondrial function in the rat |
| |
| Authors: | J W Bielecki E Pawlicka J Górski |
| |
| Affiliation: | Department of Physiology, School of Medicine, Bia?ystok. |
| |
| Abstract: | The oxidative and phosphorylative function of rat liver mitochondria after exhaustive exercise was investigated. The stimulation of state 4 respiration (without ADP) with NADH and FADH2 dependent substrates was demonstrated. The reduction in RCR ratio (the rate of oxidation in state 3/the rate of oxidation in state 4) and enhanced activity of oligomycin sensitive ATP-ase was also found. The results suggest an inhibition of liver mitochondrial phosphorylative activity in rats exercised till exhaustion. |
| |
| Keywords: | |
|
