Patient-orientated longitudinal study of multiple sclerosis in south west England (The South West Impact of Multiple Sclerosis Project,SWIMS) 1: protocol and baseline characteristics of cohort |
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| Authors: | John P Zajicek Wendy M Ingram Jane Vickery Siobhan Creanor Dave E Wright Jeremy C Hobart |
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| Institution: | 1.Clinical Neurology Research Group, Peninsula College of Medicine and Dentistry,University of Plymouth,UK;2.Department of Medical Statistics,University of Plymouth,UK |
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| Abstract: | Background There is a need for greater understanding of the impact of multiple sclerosis (MS) from the perspective of individuals with
the condition. The South West Impact of MS Project (SWIMS) has been designed to improve understanding of disease impact using
a patient-centred approach. The purpose is to (1) develop improved measurement instruments for clinical trials, (2) evaluate
longitudinal performance of a variety of patient-reported outcome measures, (3) develop prognostic predictors for use in individualising
drug treatment for patients, particularly early on in the disease course. |
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