Prostaglandins inhibit Intestinal Sodium Transport |
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| Authors: | QAIS AL-AWQATI,WILLIAM B. GREENOUGH Suffix" >III |
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| Affiliation: | 1.Department of Medicine,The Johns Hopkins University School of Medicine,Baltimore;2.Department of Medicine,Massachusetts General Hospital,Boston |
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| Abstract: | PROSTAGLANDINS1 are synthesized in the gut2 but their role, if any, on regulation of intestinal function is unknown. Oral administration of prostaglandins shortens intestinal transit time3 and several prostaglandin-producing tumours are associated with diarrhoea4. Infusion of prostaglandins and theophylline into the superior mesenteric artery of dogs results in the loss of gut fluid from jejunal loops5. |
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