|
|||||
|
|
Sulphonamide-based small molecule VLA-4 antagonists |
|
| Authors: | Stasiak Marcin Mehlin Christopher Boni Erica Vaisar Tomas Little Thomas Kim Hwa-Ok Qabar Maher |
| Institution: | Molecumetics, 2023 120th Avenue N E., Bellevue, WA 98005, USA. |
| Abstract: | The discovery of a sulphonamide by-product with VLA-4 antagonistic activity led to a series of potent, small molecule VLA-4 antagonists. Synthesis, SAR and in vivo evaluation of the selected compound will be presented. |
| Keywords: | |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |