| 细菌的核酮糖单磷酸途径与甲醛同化作用 |
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| 引用本文： | 宋中邦,陈丽梅,李昆志,潘正波.细菌的核酮糖单磷酸途径与甲醛同化作用[J].微生物学报,2007,47(1):168-172. |
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| 作者姓名： | 宋中邦 陈丽梅 李昆志 潘正波 |
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| 作者单位： | 昆明理工大学生物工程技术研究中心,昆明,650224 |
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| 基金项目： | 国家自然科学基金;教育部留学回国人员科研启动基金;云南省中青年学术与技术带头人培养费和昆明理工大学校科研和教改项目 |
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| 摘 要： | 核酮糖单磷酸途径最初在甲基营养菌中发现,现在被认为是在细菌中广泛存在的和甲醛同化作用及脱毒相关的一条途径,该途径的关键酶是6-磷酸己酮糖合成酶和6-磷酸己酮糖异构酶。文章将介绍来源于各种细菌的核酮糖单磷酸途径的生理作用及其两个关键酶基因的组织结构、表达调控机制与应用前景。
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| 关 键 词： | 甲基营养菌 核酮糖单磷酸途径 甲醛同化作用 |
| 文章编号： | 0001-6209（2007）01-0168-05 |
| 修稿时间： | 2006-06-13 |
Bacterial ribulose monophosphate pathway and formaldehyde assimilation |
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| SONG Zhong-bang,CHEN Li-mei,LI Kun-zhi and PAN Zheng-bo.Bacterial ribulose monophosphate pathway and formaldehyde assimilation[J].Acta Microbiologica Sinica,2007,47(1):168-172. |
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| Authors: | SONG Zhong-bang CHEN Li-mei LI Kun-zhi and PAN Zheng-bo |
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| Institution: | Biotechnology Research Center; Kunming University of Science and Technology; Kunming 650224; China;Biotechnology Research Center; Kunming University of Science and Technology; Kunming 650224; China;Biotechnology Research Center; Kunming University of Science and Technology; Kunming 650224; China;Biotechnology Research Center; Kunming University of Science and Technology; Kunming 650224; China |
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| Abstract: | Ribulose monophosphate pathway (RuMP), which was originally found in methylotrophic bacteria, is now recognized as a metabolic pathway widespread in most bacteria and involved in formaldehyde assimilation and detoxification. 3-Hexulose-6-phosphate synthase (HPS) and 6-phospho-3-hexuloisomerase (PHI) are the key enzymes of this pathway. This review describes the physiological significance of RuMP pathway derived from a variety of bacteria, the organizations and expressional regulations of HPS and PHI genes and the perspectives for applications of the two genes. |
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| Keywords: | Methylotrophic bacteria Ribulose monophosphate pathway Formaldehyde assimilation |
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