Small nucleolar RNAs and their genes in vertebrates |
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Authors: | J. A. Makarova D. A. Kramerov |
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Affiliation: | 1.Engelhardt Institute of Molecular Biology,Russian Academy of Sciences,Moscow,Russia |
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Abstract: | Genes of box C/D small nucleolar RNAs (snoRNAs) were searched for in the genomes of members of all classes of vertebrates that do not belong to placental mammals. A tendency for an increase in the number of copies of snoRNA genes was observed in such vertebrates. This trend was most pronounced in anamnia (amphibians and fish). Box C mutations were found in 14 snoRNAs in all gene copies among all species studied. The role of the described events is discussed. |
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