Differentiation of glucose-6-phosphate dehydrogenase isozymes and morphogenesis in blastocladiella emersonii

Summary Studies were made of some of the properties of a NADP-specific Glucose-6-phosphate dehydrogenase present in the OC and RS cells of the aquatic fungus, Blastocladiella emersonii, the former harvested at their generation time and the latter at their morphological point of no return. A more detailed analysis was then made of the distribution of soluble and bound forms of the dehydrogenase during the exponential growth and subsequent differentiation of the RS cell, as well as the changes which occurred in the isozymes of this enzyme during the same developmental period. The results, together with some related, previously published work, were discussed with emphasis on the relation between biochemical and morphological differentiation in B. emersonii.