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Growth inhibition of a MC-induced mouse sarcoma by TCGF (IL 2)-containing preparations |
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| Authors: | Bubeník J. Perlmann P. Indrová M. Šimová J. Jandlová T. Neuwirt J. |
| Affiliation: | (1) Institute of Molecular Genetics, Czechoslovak Academy of Sciences, Flemingovo 2, Prague 6, Czechoslovakia;(2) Department of Immunology, The Wenner-Gren Institute, S-106 91 Stockholm, Sweden |
| Abstract: | Summary Supernatants from Con A-stimulated rat spleen cell cultures containing T cell growth factor inhibited growth of a transplantable 3-methylcholanthrene-induced sarcoma in syngeneic mice. The tumour-inhibitory effects were dependent on the concentration of T cell growth factor and repeated injections of the supernatants. |
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