Evaluation of early embryonic mortality in donor insemination by a mathematical model,globally and depending on semen quality

Stating the probability of pregnancy per cycle as P_oP_FP_v, the product of the probabilities of ovulation, fertilization, and egg viability, the model allows an estimate of P_F and P_oP_v for a series of cycles with known insemination timing. Such results obtained from a series of donor insemination (AID) compared with those generally admitted in natural reproduction suggest that the lower pregnancy rate in AID (all the lower when the postthaw motility is low) is owing to a lower egg viability. Since the abortion rate does not seem higher, there might be a sizable rate of very early embryonic deaths in AID perhaps even as early as nondeveloping eggs.