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Calmodulin intracelluar concentration and cAMP-dependent protein kinase activity in human sperm samples in relation to sperm motphlogy and motlity
Authors:Claude C. Pariset  Claude Roussel  Serge J. Weinman  Jacques G. Demaille
Abstract:Calmodulin concentration and cAMP-dependent protein kinase activity have been determined in human sperm samples. No significant differences have been noticed in the motility index of two groups of sperm samples differing in their intracellular concentration of calmodulin. It was however found that a low intracellular clamodulin concentration is frequently associated with particular anomalies of the head and tail region. In contrast, a positive correlation has been demonstrated between the motility index and the whole extractable cAMP-dependent protein activity of the different sperm samples. In suspension s, When the cAMP-dependent protein kinase activity was measured on intact sperm suspensions, a positive correlation between the activity and the motility index was also found.
Keywords:calmodulin  cAMP-dependent protein kinases  sperm structural anomalies  cell motility
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