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Trading translation with RNA-binding proteins
Authors:Abaza Irina  Gebauer Fátima
Affiliation:Centre de Regulació Genòmica, Gene Regulation Programme, 08003 Barcelona, Spain.
Abstract:RNA-binding proteins regulate every aspect of RNA metabolism, including pre-mRNA splicing, mRNA trafficking, stability, and translation. This review summarizes the available information on molecular mechanisms of translational repression by RNA-binding proteins. By using a specific set of well-defined examples, we also describe how regulation can be reversed.
Keywords:translation   RNA-binding proteins   hnRNP K   SXL   Maskin   Cup   IRP   GAIT   CPEB   Smaug
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