Immunochemical characterisation of the myofibrillar proteinase from cultured rat myocytes as chymase |
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Authors: | R Heath J Kay L Kuehn B Dahlmann W T Stauber M Mayer |
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Affiliation: | Dept. of Biochemistry, University College, Cardiff, Wales, U.K. |
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Abstract: | The proteinase extracted from the myofibrillar fraction of (a) primary rat myocytes and (b) the L-8 myogenic cell line, both maintained in culture, was identified by immunochemical analysis as chymase, the chymotrypsin-like serine proteinase of rat mast cells. Chymase would therefore appear to be an intrinsic protein in the rat myocyte also. |
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