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Colloid Lithography-Induced Polydimethylsiloxane Microstructures and their Application to Cell Patterning
Authors:Dong Kee Yi  Min Jun Kim  Linda Turner  Kenneth S Breuer  Dong-Yu Kim
Institution:(1) Institute of Bioengineering and Nanotechnology, Singapore, 138669, Singapore;(2) Division of Engineering, Brown University, Providence, RI 02192, USA;(3) Rowland Institute at Harvard, Cambridge, MA 02142, USA;(4) Center for Frontier Materials, Gwangju Institute of Science and Technology, Gwang-Ju, 500-712, Republic of Korea
Abstract:Colloidal lithography was used to make a novel array (2-D) of micro-rings, dots, and interconnected-honeycomb structures. These geometries are controlled using the curing temperature-dependent rheological properties of the siloxane elastomer precursor. Serratia marcescens was patterned on the interconnected honeycomb microstructure demonstrating a potential application for microbioanalytical devices, microfluidics, and bio-micro-electromechanical systems. Received 26 August 2005; Revisions requested 23 September 2005; Revisions received 10 November 2005; Accepted 11 November 2005
Keywords:cell patterning  colloidal lithography  honeycomb structures  micro-rings  Serratia marcescens
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