Colloid Lithography-Induced Polydimethylsiloxane Microstructures and their Application to Cell Patterning |
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Authors: | Dong Kee Yi Min Jun Kim Linda Turner Kenneth S Breuer Dong-Yu Kim |
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Institution: | (1) Institute of Bioengineering and Nanotechnology, Singapore, 138669, Singapore;(2) Division of Engineering, Brown University, Providence, RI 02192, USA;(3) Rowland Institute at Harvard, Cambridge, MA 02142, USA;(4) Center for Frontier Materials, Gwangju Institute of Science and Technology, Gwang-Ju, 500-712, Republic of Korea |
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Abstract: | Colloidal lithography was used to make a novel array (2-D) of micro-rings, dots, and interconnected-honeycomb structures.
These geometries are controlled using the curing temperature-dependent rheological properties of the siloxane elastomer precursor.
Serratia marcescens was patterned on the interconnected honeycomb microstructure demonstrating a potential application for microbioanalytical
devices, microfluidics, and bio-micro-electromechanical systems.
Received 26 August 2005; Revisions requested 23 September 2005; Revisions received 10 November 2005; Accepted 11 November
2005 |
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Keywords: | cell patterning colloidal lithography honeycomb structures micro-rings Serratia marcescens |
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