Regression Models for Clinical Trials with Correlated Categorical Responses |
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Authors: | R T Burnett J Shedden L Broekhoven |
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Abstract: | Regression models for correlated categorical data are presented in which the covariance is a function of measured effects. The regression and covariance parameters are estimated by extended least square methods. A numerical example of a clinical trial comparing two antiemetic treatment regimes for patients receiving chemotherapy is given to illustrate the approach. |
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Keywords: | Clinical trials Estimating equations Correlated binary data Categorical responses |
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