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细菌响应过量活性氧的存活策略及相关研究进展
引用本文:张玲娜,董丽,廖红梅. 细菌响应过量活性氧的存活策略及相关研究进展[J]. 微生物学通报, 2021, 48(4): 1249-1259
作者姓名:张玲娜  董丽  廖红梅
作者单位:1 江南大学食品学院 江苏 无锡 214122;2 中国农业大学食品科学与营养工程学院 北京 100083
基金项目:国家自然科学基金(31471714,31101360)
摘    要:活性氧(Reactive Oxygen Species,ROS)是指基态氧分子获取电子后形成的一类具有高反应活性的物质.有氧呼吸电子传递链产生的内源ROS能维持细菌正常生理活性,而由消毒、抗生素和物理场等处理产生的外源ROS会随着处理时间和强度增加而累积产生.过量ROS会给细菌带来氧化压力,导致氧化损伤,甚至影响其活性...

关 键 词:细菌  活性氧  氧化损伤  存活策略

Survival strategies of bacteria in response to excessive reactive oxygen species: a review
ZHANG Lingn,DONG Li,LIAO Hongmei. Survival strategies of bacteria in response to excessive reactive oxygen species: a review[J]. Microbiology China, 2021, 48(4): 1249-1259
Authors:ZHANG Lingn  DONG Li  LIAO Hongmei
Affiliation:1 School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China;2 College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China
Abstract:Reactive oxygen species (ROS) refers to a category of highly reactive substances formed by ground-state oxygen molecules acquiring electrons. ROS can be generated by aerobic respiration electron transport chain that helps maintain normal physiological activity of bacteria. Lots of exogenous ROS are generated and accumulated during cleaning and disinfection, medical treatment, etc. Excessive ROS would bring oxidative stress, lead to oxidative damage, and even affect activities of bacteria. In this review, we analyze the oxidative stress response induced by excessive ROS, the correlation between excessive ROS and the formation, recovery or repair of special non-spore status of bacteria, and even leading to their death, to provide reference for the innovation of effective control of spoilage and pathogenic bacteria.
Keywords:bacteria   reactive oxygen species   oxidative stress   survival strategy
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