A case of glucocorticoid-suppressible hyperaldosteronism with aldosterone producing adenoma |
| |
Authors: | S Kato M Haji T Yanase H Nawata K Kato H Ibayashi |
| |
Affiliation: | Third Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan. |
| |
Abstract: | A 34-yr-old woman with hypertension (142/102 mmHg), hypokalemia, high plasma and urinary aldosterone and low plasma renin activity was studied. A left adrenal tumor and enlarged right adrenal gland were demonstrated by adrenal venography. During administration of dexamethasone (2 mg daily, for 3 weeks), urinary aldosterone excretion decreased abruptly from 22.5 to 9-11 micrograms/day, serum potassium increased and blood pressure fell to 120-130/80-90 mmHg. After left adrenalectomy, all manifestations improved with no medication. The resected adrenal gland revealed clear cell adenoma and micronodular adrenocortical hyperplasia. The patient was considered to be a rare case of glucocorticoid-suppressible hyperaldosteronism with an aldosterone-producing adenoma. |
| |
Keywords: | |
|
|