Trends in colorectal cancer incidence and related lifestyle risk factors in 1549-year-olds in Canada, 19692010 |
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Institution: | 1. The Jiading District Center for Disease Control and Prevention, Shanghai 201800, China;2. Fudan University School of Public Health, Building 8, 130 Dong''an Road, Xuhui District, Shanghai 200032, China;3. Key Laboratory of Public Health Safety, Fudan University, Ministry of Education, Building 8, 130 Dong An Road, Xuhui District, Shanghai 200032, China;4. Fudan University Center for Tropical Disease Research, Building 8, 130 Dong''an Road, Xuhui District, Shanghai 200032, China;5. School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada;6. Traffic Command Center, Municipal Transportation Commission, Shanghai 200051, China |
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Abstract: | BackgroundWhile the overall incidence rate of colorectal cancer (CRC) in Canada has been decreasing, some countries show an increasing incidence in those under the age of 50. We examined the trends in CRC incidence and associated lifestyle risk factors in Canadians aged 1549.MethodsIncidence data for colorectal, colon and rectum/rectosigmoid cancers were obtained for 19692010 from the Canadian Cancer Registry, and trends in age-standardized incidence rates (ASIRs) were examined by Joinpoint regression for three age groups (1529, 3039, 4049 years) and by sex. Trends in the prevalence of some CRC risk factors were similarly examined from national health surveys for various periods ranging from 1970 to 2012.ResultsIn both sexes combined, ASIRs rose by 6.7%/year (19972010) for 1529-year-olds, 2.4%/year (19962010) for 3039-year-olds, and 0.8%/year (19972010) for 4049-year-olds. Similar trends were observed by sex. The rise in ASIR was more rapid for cancers of the rectum/rectosigmoid compared to colon for all age groups. Risk factor trends varied: excess weight rose substantially, vegetables and fruit consumption increased slightly, physical inactivity rates declined but remained high, alcohol consumption changed little, and smoking rates declined. Data on red/processed meat consumption were unavailable.ConclusionThe ASIR of CRC in young Canadians has increased since about the mid-1990s. The rising prevalence of excess weight in younger generations has likely played a role in the CRC trend, but more research is needed. |
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Keywords: | Colorectal cancer Incidence Young adults Risk factors Canada |
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