Characterization of protein-interaction networks in tumors |
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| Authors: | Alexander Platzer Paul Perco Arno Lukas Bernd Mayer |
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| Institution: | (1) Institute for Theoretical Chemistry, University of Vienna, Waehringer Strasse 17, A-1090 Vienna, Austria;(2) emergentec biodevelopment GmbH, Rathausstrasse 5/3, A-1010 Vienna, Austria |
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| Abstract: | Background Analyzing differential-gene-expression data in the context of protein-interaction networks (PINs) yields information on the
functional cellular status. PINs can be formally represented as graphs, and approximating PINs as undirected graphs allows
the network properties to be characterized using well-established graph measures. |
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