Identity Between Cytoplasmic and Membrane-Bound S-100 Proteins Purified from Bovine and Rat Brain |
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Authors: | Rosario Donato Bruno Prestagiovanni Giovanni Zelano |
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Affiliation: | Institute of Anatomy, Medical School, Perugia;Institute of Anatomy, UniversitàCattolica, Roma, Italy |
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Abstract: | Cytoplasmic and membrane-bound S-100 proteins were purified to homogeneity from bovine and rat brain. Cytoplasmic and membrane-bound S-100 from single species are identical by immunological, electrophoretic, spectrophotometric, and functional criteria. Cytoplasmic and membrane-bound S-100 from bovine brain consists of nearly equal amounts of S-100a and S-100b, whereas cytoplasmic and membrane-bound S-100 from rat brain consists mostly of S-100b. The functional role of membrane-bound S-100 remains to be elucidated. |
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Keywords: | Cytoplasmic S-100 Membrane-bound S-100 Purification Identity |
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