The effect of camphor on bacterial bioluminescence |
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Authors: | Vadim Danilov Nina Baranova Anvar Ismailov Nicolai Egorov |
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Institution: | (1) Microbiological Department, M. V. Lomonosov State University, 117234 Moscow, USSR |
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Abstract: | Summary The inhibitory effect of camphor on bioluminescence of both bacteria and bacterial luciferase has been examined. The camphor has been shown to be a substrate of cytochrome P-450 of the luminous bacteria Photobacterium fischeri. The inhibition of the luminescence reaction provided evidence for the competitive nature of the interaction of camphor and aliphatic aldehyde at the binding site for luciferase. Camphor is also supposed to interact with P-450. The findings indicate that the hydroxylation process of camphor affects the kinetics of the luminescence. |
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