Centrosome biogenesis: centrosomin sizes things up! |
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Authors: | Gomez-Ferreria Mariana Pelletier Laurence |
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Institution: | Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, M5G 1X5, Canada. |
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Abstract: | Centrosomes are composed of a centriole pair surrounded by a proteinaceous matrix of pericentriolar material that contains protein complexes required for microtubule nucleation and anchoring. Recent work reveals an intriguing link between centrioles and pericentriolar material that is involved in modulating centrosome size. |
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