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Standardization and quality control of Leishmania tropica vaccine
Authors:E Handman  D T Spira  A Zuckerman  B Montilio
Affiliation:1. Department of Microbiology and Molecular Medicine, CMU, University of Geneva, Geneva, Switzerland;2. Department of Biochemistry, University of Cambridge, Cambridge CB2 1QW, UK;1. Medicines for Malaria Venture, Geneva, Switzerland;2. Global Antibiotic Research and Development Partnership, Geneva, Switzerland;3. Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA;4. Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA;1. Institute of Medical Microbiology and Hospital Hygiene, Otto-von-Guericke University of Magdeburg, Magdeburg, Germany;2. Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany
Abstract:The production and properties of Leishmania tropica vaccine have been described. It has been pointed out that the use of this vaccine is not without inherent hazards and great care should be taken in its preparation. A set of requirements for the production and testing of the vaccine based on those of the Ministry of Health in Israel and the U.S. Department of Health is suggested.
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