Notes The ribonucleoside diphosphate reductase gene (nrdA) of Escherichia coli carries a repetitive extragenic palindromic (REP) sequence in its 3'structural terminus |
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| Authors: | E. Merino F. Bolivar |
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| Affiliation: | Centro de Investigación sobre Ingeniería Genética y, Biotechnología, Universidad Nacional Autónoma de Mexico, Cuernavaca, Morelos C.P. |
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| Abstract: | A computer search for repeated sequences led us to identify five REP (repetitive extragenic palindromic) sequences in the 3'-terminal region of the Escherichia coli ribonucleoside diphosphate reductase gene (nrdA). These REP sequences are located within a putative duplicated DNA region, the first of them being part of the carboxy-terminal coding region of the nrdA gene. This is the first report of a REP sequence within a structural gene and also the first example of a REP sequence apparently generated by DNA duplication. |
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