98.55W/cm2脉冲微波辐照对大鼠血清生化指标影响的研究

二级雄性Wistar大鼠35只，随机分为7组，每组5只，1组为空白对照，其余6组为辐照组以98.55W/cm^2的脉冲微波辐照动物，辐照后1、6、24h和7、14、28d分别采血，用Coulter-JTIR全自动生化仪进行测定，所有数据经Spss8.0统计软件处理，辐射后1h，CRE明显增高（P＜0.01），而TP、ALB、AST、LD1、CK、ALP及CHOL均明显降低（P＜0.05）；辐射后6h，春CRE明显增高（P＜0.05），而TP、ALB、LD1、ALP及CHOL均明显降低（P＜0.05）；辐照后24h，其ALT、GLU、BUN、CRE、AST、LD和HBDH明显升高（P＜0.05），而LB和CHOL则明显降低（P＜0.05）；辐照后7d，其ALT、ALB、GLU、CRE、CK－MB和GGT明显升高（P＜0.05），而P和CHOL则明显降低（P＜0.05)；辐照后14d，其CRE、LD、CK－MB和GGT明显升高（P＜0.05），而P和CHOL则明显降低（P＜0.01）；辐照后28d，其ALT、TP、BUN和CRE明显升高（P＜0.05），而ALB、AST、LD1、CK、ALP和CHOL则明显降低（P＜0.01）。提示HPPMW可引起大鼠血清多种酶、蛋白及代谢产物的紊乱，即有早期影响，也表现为一定的持续效应。HPPMW可能引起大鼠多系统、多脏器的损伤。

Changes on the Serum Biochemical Indexes in Rats Irradiated by 98.55W/cm2 Pulse Microwave

Thirty-five male Wistar rats were randomly divided into seven groups. A control group and six HPPMW groups. HPPMW groups were irradiated by 98.55?W/cm 2 HPPMW strength 2 pulses within 5 minutes respectively, no treat to contrast group. The left ventricle blood was sarnpled at 1, 6, 24 h and 7, 14, 28 d after irradiation, and were measured by Coulter-JTIR automatic biochemical analyzer. All data was analyzed by statistical softwareSpss8.0. The results suggested that a flucturation of the biochemical indexes in rat serum could be induced by HPPMW, which showed some early stage effects and durative effects. It is inferred that HPPMW could injure many organs and systems of rats.