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The molecular genetics of C1 utilizing microorganisms an overview
Authors:B. W. Holloway  P. P. Kearney  B. R. Lyon
Affiliation:(1) Department of Genetics, Monash University, 3168 Clayton, Victoria, Australia;(2) The Galton Laboratory, Department of Genetics and Biometry, University College of London, NW1 2HE London, UK
Abstract:The availability of recombinant DNA techniques has enabled the successful genetic analysis and manipulation of a range of C1 utilizing microorganisms. It has resulted in the identification of genes of interest on both plasmids and the chromosome; enabled the linkage of chromosomal genes to be determined; established the function and regulatory patterns of genes essential for utilization of C1 compounds and provided information on the evolution of methanogenic bacteria.
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