Phenylacetyl-Coenzyme A Is the True Inducer of the Phenylacetic Acid Catabolism Pathway in Pseudomonas putida U |
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| Authors: | Bel n Garcí a, Elí as R. Olivera, Baltasar Mi ambres, David Carnicero, Carmen Mu iz, Germ n Naharro, Jos M. Luengo |
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| Affiliation: | Belén García, Elías R. Olivera, Baltasar Miñambres, David Carnicero, Carmen Muñiz, Germán Naharro, and José M. Luengo |
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| Abstract: | Aerobic degradation of phenylacetic acid in Pseudomonas putida U is carried out by a central catabolism pathway (phenylacetyl-coenzyme A [CoA] catabolon core). Induction of this route was analyzed by using different mutants specifically designed for this objective. Our results revealed that the true inducer molecule is phenylacetyl-CoA and not other structurally or catabolically related aromatic compounds. |
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