LOX out, histones: a new enzyme is nipping at your tails |
| |
Authors: | Black Joshua C Whetstine Johnathan R |
| |
Institution: | Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Charlestown, MA 02129, USA. |
| |
Abstract: | In the current issue of Molecular Cell, Herranz et al. (2012) demonstrate that LOXL2 deaminates trimethylated histone 3 lysine 4 (H3K4me3), which uncovers a new chromatin modification and a new enzymatic mechanism with the potential to regulate additional lysine residues. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|