Department of Molecular Genetics, Biochemistry, and Microbiology, College of Medicine, University of Cincinnati, OH 45267, USA.
Abstract:
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Highlights? Structure of dimeric apoA-IV solved to 2.4 Å by X-ray crystallography ? Structure confirmed through biochemical and mutational analysis ? Understanding of apoA-IV dimerization allowed us to create a monomeric mutant ? Structural features in the dimer offer clues to the genesis of apoA-IV lipoproteins
