Synthesis of a series of novel 2,5-disubstituted-1,3,4-oxadiazole derivatives as potential antioxidant and antibacterial agents |
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| Authors: | M Aruna Sindhe Yadav D Bodke R Kenchappa Sandeep Telkar A Chandrashekar |
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| Institution: | 1.Department of P.G. Studies and Research in Industrial Chemistry, Jnana Sahyadri,Kuvempu University,Shivamogga,India;2.Department of P.G. Studies and Research in Biotechnology, Jnana Sahyadri,Kuvempu University,Shivamogga,India |
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| Abstract: | A series of novel 2,5-disubstituted-1,3,4-oxadiazole derivatives were synthesized and screened for their antimicrobial and antioxidant activities. The assay indicated that compounds 3c, 3d, and 3i exhibited comparable antibacterial and antioxidant activity with first-line drugs. The structure activity relationship and molecular docking study of the synthesized compounds are also reported. |
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