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Database and interaction network of genes involved in oral cancer: Version II
Authors:Gadewal Nikhil Sureshkumar  Zingde Surekha Mahesh
Affiliation:1Bioinformatics centre (BTIS Sub-DIC), ACTREC, Kharghar, Navi Mumbai 410210, India;2Advanced Centre for Treatment Research and Education in Cancer, Tata Memorial Centre, Kharghar, Navi Mumbai, 410210, India
Abstract:The oral cancer gene database has been compiled to enable fast retrieval of updated information and role of the genes implicated in oral cancer. The first version of the database with 242 genes was published in Online Journal of Bioinformatics 8(1), 41-44, 2007. In the second version, the database has been enlarged to include 374 genes by adding 132 gene entries. The architecture and format of the database is similar to the earlier version, and includes updated information and external hyperlinks for all the genes. The functional gene interaction network for important biological processes and molecular functions has been rebuilt based on 374 genes using 'String 8.3'. The database is freely available at http://www.actrec.gov.in/OCDB/index.htm and provides the scientist information and external links for the genes involved in oral cancer, interactions between them, and their role in the biology of oral cancer along with clinical relevance.
Keywords:Oral cancer   Database   Gene interaction network
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