NK cell lymphoma, nasal type, with massive lung involvement: a case report |
| |
| Authors: | Morovic Anamarija Aurer Igor Dotlic Snjezana Weisenburger Dennis D Nola Marin |
| |
| Institution: | 1.Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267 USA ;2.Department of Internal Medicine, Zagreb University Hospital Center, Kispaticeva 12, Zagreb, 10000 Croatia ;3.Department of Pathology and Microbiology, University of Nebraska Medical Center, 983135 Nebraska Medical Center, Omaha, NE 68198 USA ;4.Department of Pathology, Zagreb University Hospital Center, Kispaticeva 12, Zagreb, 10000 Croatia |
| |
| Abstract: | Extranodal NK/T cell lymphoma, nasal type, is an Epstein–Barr virus-associated lymphoma that most commonly involves the nasal cavity and upper respiratory tract. Lung involvement by NK/T cell lymphoma is rare and seldom reported in the literature. We describe the unusual case of a 41-year-old male with NK cell lymphoma, nasal type, who presented with massive secondary lung involvement 2.5 years after the detection of a retroperitoneal mass. The diagnosis was made by open lung biopsy. Despite aggressive treatment, the patient died shortly after the initiation of therapy. Lung involvement by NK/T cell lymphoma occurs most commonly as part of widely disseminated disease and carries a poor prognosis for the patient. Novel agents and innovative therapies need to be developed for this aggressive lymphoma. |
| |
| Keywords: | Extranodal NK/T lymphoma Lung involvement Epstein–Barr virus |
| 本文献已被 PubMed 等数据库收录！ |
|
