| 核糖核酸酶基因超家族分子进化 |
| |
| 引用本文： | 郎大田,张亚平,于黎.核糖核酸酶基因超家族分子进化[J].遗传,2014,36(4):316-326. |
| |
| 作者姓名： | 郎大田 张亚平 于黎 |
| |
| 作者单位： | 1. 云南大学, 云南省生物资源保护与利用重点实验室, 昆明 650091;
2. 云南大学, 云南省高校动物遗传多样性与进化重点实验室, 昆明 650091;
3. 中国科学院昆明动物研究所, 遗传资源与进化国家重点实验室, 昆明 650223 |
| |
| 基金项目： | 新世纪优秀人才支持计划项目;中组部青年拔尖人才支持计划资助 |
| |
| 摘 要： | 核糖核酸酶基因(Ribonuclease A, RNASE A)超家族是进化生物学中研究新基因起源及新功能演变的重要模式系统之一。RNASE A超家族中的很多成员表现出基因复制的进化模式, 而且在适应性(正)选择的驱动下, 发生了功能分化。文章综述了RNASE A超家族成员在不同动物类群中进化模式的研究进展, 包括近年来越来越多在基因组水平上开展的相关研究, 显示该基因超家族可能具有比人们以往认识的更为复杂的基因进化模式。随着越来越多动物基因组数据的产生, 对更多动物代表类群进行RNASE A超家族研究, 将有望揭示新的进化机制和功能分化, 为系统认识动物适应进化的遗传机制奠定基础。
|
| 关 键 词： | 核糖核酸酶基因超家族 适应性进化 基因复制 功能分化 基因组 |
| 收稿时间： | 2013-11-19 |
Molecular evolution of the ribonuclease A superfamily |
| |
| Institution: | 1. Laboratory for Conservation and Utilization of Bio-resource, Yunnan University, Kunming 650091, China;
2. Key Laboratory for Animal Genetic Diversity and Evolution of High Education in Yunnan Province, Yunnan University, Kunming 650091, China;
3. State Key Laboratory of Genetics Resource and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China |
| |
| Abstract: | Ribonuclease A (RNASE A) superfamily is one of the model systems for studying new gene origin and functional innovations in evolutionary biology. Remarkably, gene duplications have been found in many members of RNASE A superfamily, and the functional differentiations of the duplicated genes have been demonstrated to be driven by the adaptive (positive) selection. In this review, we summarize the researches on the evolutionary patterns of RNASE A genes in differ-ent species, especially the recent researches at the genomic levels, suggesting a far more complex and intriguing evolution-ary diversity of RNASE A than previously thought. In the future, along with the increasing numbers of animal genomes available, the studies of RNASE A from more species are expected to reveal new evolutionary patterns and functional di-versifications, which will lay a foundation for the systematic studies on the molecular basis of adaptive evolution. |
| |
| Keywords: | |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《遗传》浏览原始摘要信息 |
| 点击此处可从《遗传》下载免费的PDF全文 |
|
