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Localized expression pattern of miR-184 in <Emphasis Type="Italic">Drosophila</Emphasis>
Authors:Ping Li  Jianjian Peng  Jiangbo Hu  Zhongxin Xu  Wei Xie  Liudi Yuan
Institution:(1) Key Laboratory of Developmental Genes and Human Disease, Ministry of Education, Southeast University, Nanjing, 210009, People’s Republic of China;(2) Institute of Life Science, Southeast University, Nanjing, 210009, People’s Republic of China;
Abstract:MicroRNAs (miRNAs) are a kind of endogenous non-coding small RNAs whose specific functions in animals are generally important. Although functions of some miRNAs have been identified, the role of miR-184 remains unknown. Here, we determined the temporal and spatial expression pattern of miR-184 during the different development stages and tissues in Drosophila. Strikingly, miR-184 is expressed ubiquitously in Drosophila embryos, larvae and adults, its expression pattern shows a dynamic changes during the development of embryo, especially in the central nervous system. This expression profile suggests that miR-184 may act important function in Drosophila development.
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