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Analysis of survival data with cross-effects of survival functions |
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| Authors: | Bagdonavicius Vilijandas Hafdi Mohamed A Nikulin Mikhail |
| Affiliation: | Department of Mathematical Statistics, University of Vilnius, Naugarduko 24, Vilnius, Lithuania. |
| Abstract: | We present a model and semiparametric estimation procedures for analysis of survival data with cross-effects (CE) of survival functions. Finite sample properties of the estimators are analyzed by simulation. A goodness-of-fit test for the proportional hazards model against the CE model is proposed. The well known data concerning effects of chemotherapy and radiotherapy on the survival times of gastric cancer patients is analyzed as an example. |
| Keywords: | CE model Chemotherapy Chi-squared type test Cross-effects Gastric cancer data Gastrointestinal tumor GPH model Hougaard– Aalen model Hsieh Model PH model Radiotherapy Semiparametric likelihood Survival |
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