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Curation of the Plasmodium falciparum genome
Authors:Berry Andrew E  Gardner Malcolm J  Caspers Gert-Jan  Roos David S  Berriman Matthew
Institution:Pathogen Sequencing Unit, Wellcome Trust Sanger Institute, Hinxton Hall, Cambridge CB10 1SA, UK. aeb@sanger.ac.uk
Abstract:The malaria genome has proved invaluable to researchers worldwide in the continuing fight against malaria by stimulating and underpinning molecular approaches in gene expression studies, vaccine and drug discovery research, and by providing data to facilitate hypothesis-driven research. The combination of in silico and experimental investigations has already yielded dividends by strengthening our understanding of the many facets of the malaria parasite Plasmodium falciparum. The recently initiated curation of the genome resource is a vital investment for maintaining and enhancing the use of this genomic information in the post-genomic era.
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