A new cap for kinetochore fibre minus ends |
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| Authors: | Petry Sabine Vale Ronald D |
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| Affiliation: | Howard Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California 94158, USA. |
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| Abstract: | In mitotic spindles, each sister chromatid is directly attached to a spindle pole through microtubule bundles known as kinetochore fibres. Microspherule protein 1 (MCRS1) is now shown to support spindle assembly by localizing to the minus ends of kinetochore fibres and protecting them from depolymerization. |
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