| 激光所致核酸损伤的分子机制 |
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| 引用本文： | 杨素红,葛忠良.激光所致核酸损伤的分子机制[J].激光生物学报,1992,1(4):178-181,190. |
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| 作者姓名： | 杨素红 葛忠良 |
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| 作者单位： | 北京放射医学研究所 北京
(杨素红)，北京放射医学研究所 北京(葛忠良) |
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| 摘 要： | 本文综述了近来有关紫外激光诱导核酸损伤(主要是碱基损伤、单链断裂和双链断裂)形成的化学过程的文献报导,主要是讨论了双光子激发核酸碱基,致使核酸产生单链断裂和双链断裂的光致电离过程,以及由此归纳出来的激光诱导核酸链断裂的化学模型
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| 关 键 词： | 激光辐照 核酸损伤 |
MOLECULAR MECHANISM OF NUCLEIC ACID DAMAGE INDUCED BY LASER |
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| Yang Suhong Ge Zhongliang.MOLECULAR MECHANISM OF NUCLEIC ACID DAMAGE INDUCED BY LASER[J].ACTA Laser Biology Sinica,1992,1(4):178-181,190. |
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| Authors: | Yang Suhong Ge Zhongliang |
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| Institution: | Beijing Institute of Radiation Medicine |
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| Abstract: | Papers reported in recent years were reviewed, which are about the chemical processes of nucleic acid damages induced by ultralviolet laser(main-ly base damage, single-and douale-strand breaks). The biphotonic photoion-ization of bases and formation of SSB and DSB were discussed. The chemical models were alse commented upon nucleic acid strand breaks induced by laser. |
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| Keywords: | laser radiation photoionization nucleic acid strand break |
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