Influence of rapeseed oil feeding on the lipase activities of rat heart. |
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Authors: | H Jansen W C Hülsmann A Zuylen-van Wiggen C B Struijk U M Houtsmuller |
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Institution: | 1. Department of Biochemistry I, Faculty of Medicine, Erasmus University Rotterdam The Netherlands;2. Unilever Research, Vlaardingen, The Netherlands |
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Abstract: | Feeding high doses of fat increases the lipase activity of rat heart. The heparin-releasable activity in the hearts of rapeseed oil-fed rats remains high after prolonged feeding (10 days), whereas this activity in olive oil fed rats returns to normal values in the same period. After 10 days rapeseed oil feeding the non-releasable lipase activity in the hearts is enhanced significantly, when compared to the activity measured after 3 days. The results suggest an adaptation of heart lipases to dietary fat. |
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