The age of Alu subfamilies |
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Authors: | Vladimir Kapitonov Jerzy Jurkal |
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Institution: | (1) Linus Pauling Institute of Science and Medicine, 440 Page Mill Road, 94306 Palo Alto, CA, USA;(2) Institute of Cytology and Genetics, Lavrentyeva 10, 630090 Novosibirsk, Russia |
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Abstract: | Using Kimura's distance measure we have calculated the average age of all major Alu subfamilies based on the most recent available data. We conclude that AluJ sequences are some 26 Myr older than previously thought. Furthermore, the origin of the FLA (Free Left Arm) Alu family can be traced back to the very beginning of the mammalian radiation.One new minor subfamily is reported and discussed in the context of sequence diversity in major Alu subfamilies.
Correspondence to: J. Jurka |
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Keywords: | Alu repeats Subfamilies Repetitive DNA Molecular evolution Primates |
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