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Histopathological cutaneous alterations in systemic sclerosis: a clinicopathological study |
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| Authors: | Jens T Van Praet Vanessa Smith Marc Haspeslagh Nele Degryse Dirk Elewaut Filip De Keyser |
| Institution: | (1) Department of Rheumatology, Ghent University Hospital, De Pintelaan 185, BE-9000 Gent, Belgium;(2) Department of Dermatology, Ghent University Hospital, De Pintelaan 185, BE-9000 Gent, Belgium;(3) Department of Pathology, Stedelijk Ziekenhuis Roeselare, Brugsesteenweg 90, BE-8800 Roeselare, Belgium |
| Abstract: | IntroductionThe aims of the present study were to identify histopathological parameters which are linked to local clinical skin disease at two distinct anatomical sites in systemic sclerosis (SSc) patients with skin involvement (limited cutaneous systemic sclerosis (lcSSc) or diffuse cutaneous systemic sclerosis (dcSSc)) and to determine the sensitivity of SSc specific histological alterations, focusing on SSc patients without clinical skin involvement (limited SSc (lSSc)). |
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