Identification of new quantitative trait Loci (other than the PRNP gene) modulating the scrapie incubation period in sheep |
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| Authors: | Moreno C R Cosseddu G M Schibler L Roig A Moazami-Goudarzi K Andreoletti O Eychenne F Lajous D Schelcher F Cribiu E P Laurent P Vaiman D Elsen J M |
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| Institution: | INRA, UR 631 Amélioration Génétique des Animaux, BP52627, 31326 Castanet-Tolosan, France. moreno@toulouse.inra.fr |
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| Abstract: | Although susceptibility to scrapie is largely controlled by the PRNP gene, we have searched for additional genomic regions that affect scrapie incubation time in sheep, using two half-sib families with a susceptible PRNP genotype and naturally infected by scrapie. Quantitative trait loci were detected on OAR6 and OAR18. |
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