Collective migration: spatial tension relief |
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Authors: | Wood Jenifer M Olson Michael F |
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Affiliation: | Beatson Institute for Cancer Research, Garscube Estate, Glasgow G61 1BD, UK. |
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Abstract: | Collective epithelial cell migration facilitates formation and maintenance of continuous sheets that line the surfaces and cavities of glands and tissues. By screening Rho GTPase regulators, myosin-IXA RhoGAP was identified as a key requirement for cell-cell adhesions that permit collective migration. |
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