| Effect of Prolactin on Gonadotropin Regulation of Mouse Ovarian Function |
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| 作者姓名： | 胡召元 刘以训 |
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| 作者单位： | State Key Laboratory of Reproductive Biology Institute of Zoology Academia Sinica Beijing 100080，State Key Laboratory of Reproductive Biology Institute of Zoology Academia Sinica Beijing 100080 |
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| 基金项目： | The project is supported by Chinese Academy of Sciences，The State Family Planning Commission，The Natural Science Foundation of china，Rockefeller Foundation,New York. |
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| 摘 要： | We have demonstrated that prolactin inhibits gonadotropin-induced ovulation in PMSG-primed mice.The number of ova in oviducts considerably decreased in the group of hCG plus prolactin (PRL)(19.7 + 4.9) as compared with that of hCG alone (31.7 + 6.7). PRL inhibition of hCG-inducedovulation in mice may be through decreasing the ovarian plasminogen activator (PA) activity on onehand, and inhibiting the preovulatory increase in estrogen (E) secretion on the other.
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Effect of Prolactin on Gonadotropin Regulation of Mouse Ovarian Function |
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| HU Zhao-yuan LIU Yi--xun State Key Laboratory of Reproductive Biology.Effect of Prolactin on Gonadotropin Regulation of Mouse Ovarian Function[J].Genomics Proteomics & Bioinformatics,1993(2). |
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| Authors: | HU Zhao-yuan LIU Yi--xun State Key Laboratory of Reproductive Biology |
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| Institution: | HU Zhao-yuan LIU Yi--xun State Key Laboratory of Reproductive Biology,Institute of Zoology,Academia Sinica,Beijing 100080 |
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| Abstract: | We have demonstrated that prolactin inhibits gonadotropin-induced ovulation in PMSG-primed mice. The number of ova in oviducts considerably decreased in the group of hCG plus prolactin (PRL) (19.7 + 4.9) as compared with that of hCG alone (31.7 + 6.7). PRL inhibition of hCG-induced ovulation in mice may be through decreasing the ovarian plasminogen activator (PA) activity on one hand, and inhibiting the preovulatory increase in estrogen (E) secretion on the other. |
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| Keywords: | Prolactin Mouse Ovulation Plasminogen Activator Estrogen |
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