Intravital-microscopic observations on the intravascular behavior of blood cell components during dietary-induced hyperlipidemia in the male rabbit |
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| Authors: | M Asano C Ohkubo A Hirokawa A Sasaki Y Tochihara Y Chiba |
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| Affiliation: | Department of Physiological Hygiene, Institute of Public Health, Tokyo, Japan. |
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| Abstract: | In normal male rabbits loaded dietary cholesterol, intravital-microscopy revealed a marked acceleration of intravascular adhesiveness of white blood cells and aggregability of red blood cells and a swarming of lipid-laden macrophages in connective tissue space concurrently with a systemic hyperlipidemia and anemia. Possible roles of the microcirculatory changes in the atherogenesis were discussed. |
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