Na+-independentl-aspartate binding sites in chick brain |
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Authors: | Georgia Voukelatou Elias D Kouvelas |
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Institution: | (1) Department of Physiology, School of Medicine, University of Patras, 26110 Patras, Greece |
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Abstract: | 1. One binding component with aK
d value of 200×10–9 M and half-life of the ligand binding component of 30 min was found. 2. Chloride ions produced a significant increase ofl-3H]aspartate andl-3H]glutamate binding. 3.l-Glutamate,l-ibotenate,l-quisqualate, anddl-homocysteic acid were potent inhibitors ofl-3H]aspartate binding. 4. In all brain regions major increases of binding were observed during the third week of the in ovo period of life. |
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Keywords: | l-Aspartate binding" target="_blank">l-Aspartate binding chick brain pharmacology development |
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