Localized <Emphasis Type="Italic">rbp4</Emphasis>expression in the yolk syncytial layer plays a role in yolk cell extension and early liver development |
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| Authors: | Zhen Li Vladimir Korzh Zhiyuan Gong |
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| Institution: | (1) Department of Biological Sciences, National University of Singapore, Singapore, Singapore;(2) Laboratory of Fish Developmental Biology, Institute of Molecular and Cell Biology, Singapore, Singapore;(3) Computation and System Biology Program, Singapore-MIT Alliance, National University of Singapore, Singapore, Singapore |
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| Abstract: | Background The number of genes characterized in liver development is steadily increasing, but the origin of liver precursor cells and
the molecular control of liver formation remain poorly understood. Existing theories about formation of zebrafish visceral
organs emphasize either their budding from the endodermal rod or formation of independent anlage followed by their later fusion,
but none of these is completely satisfactory in explaining liver organogenesis in zebrafish. |
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