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Gene function and expression level influence the insertion/fixation dynamics of distinct transposon families in mammalian introns
Authors:Manuela Sironi   Giorgia Menozzi   Giacomo P Comi   Matteo Cereda   Rachele Cagliani   Nereo Bresolin  Uberto Pozzoli
Affiliation:(1) Scientific Institute IRCCS E Medea, Bioinformatic Lab, Via don L Monza, 23842 Bosisio Parini, LC, Italy;(2) Dino Ferrari Centre, Department of Neurological Sciences, University of Milan, IRCCS Ospedale Maggiore Policlinico, Mangiagalli and Regina Elena Foundation, 20100 Milan, Italy
Abstract:

Background  

Transposable elements (TEs) represent more than 45% of the human and mouse genomes. Both parasitic and mutualistic features have been shown to apply to the host-TE relationship but a comprehensive scenario of the forces driving TE fixation within mammalian genes is still missing.
Keywords:
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