Vaccination against Taenia solium cysticercosis in pigs using native and recombinant oncosphere antigens. |
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Authors: | A Plancarte A Flisser C G Gauci M W Lightowlers |
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Affiliation: | Departamento de Microbiología y Parasitología, Facultad de Medicina, UNAM, D.F., Mexico. |
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Abstract: | Pigs were immunised with antigens derived from Taenia solium oncospheres or with a pool of three recombinant antigens from Taenia ovis, and subsequently challenged with T. solium eggs. The native oncosphere antigens induced 83% protection against viable, and 89% protection against the total number of cysticerci established following the challenge infection. Immunisation with the recombinant T. ovis antigens induced 93% protection against the establishment of viable cysticerci, and 74% protection against the total number of cysticerci. These results, and those achieved elsewhere with Taenia saginata and T. ovis, support the possibility of developing a practical vaccine to assist in the control of transmission of T. solium through pigs. |
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