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Direct measurement of the force between two lipid bilayers and observation of their fusion
Authors:Roger G. Horn
Affiliation:Research School of Physical Sciences, Australian National University, GPO Box 4, Canberra, ACT 2601 Australia
Abstract:The force between two phosphatidylcholine bilayers is measured as a function of their separation, showing a strong hydration repulsion at short range, as previously reported by LeNeveu et al. (LeNeveu, D.M., Rand, R.P., Parsegian, V.A. and Gingell, D. (1977) (Biophys. J. 18, 209–230). The experimental technique also allows direct observation of the molecular process by which two bilayers fuse into one.
Keywords:Bilayer interaction  Membrane fusion  Hydration repulsion  DLPC  dilaurylphosphatidylcholine  egg-PC  egg-yolk phosphatidylcholine (egg lecithin)
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